Molecular Modification of ZnO Surface
Ken-ichi OGATA, Kazuto KOIKE, Yasuyuki HIRATA, Shigehiko SASA, Masataka INOUE and Mitsuaki YANO
Abstract:Toward the fabrication of biosensing medical devices with enzyme-modified field effect transistors based on zinc oxide (ZnO), surface modifications using organic molecules were employed. In case of molecules containing thiol groups, it was found that molecules on ZnO surfaces were desorbed during water immersion, while ZnO surfaces modified by a silane-coupling agent were stable in water. Glucoseoxidase (GOX), an enzyme, specifically reacting with glucose, could be immobilized on molecular modified ZnO surfaces. Key Words:Biosensor, Enzyme modified field effect transistor, ZnO, Surface modification, Organic molecule